Well, it's a question of whether you're on the giving or recieving end. (Also possible elemental resistances, but for the purposes of argument let's assume those aren't a factor) It's not a huge quantitative difference, but in D&D and most of the systems it inspired the difference between having one hit point left and zero is the difference between being able to act normally and lying on the floor waiting for someone to stop you from bleeding to death.
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‎noli esse culus
‎noli esse culus